Manuel Litchman, M.D.
President, Chief Executive Officer and Director
Dr. Litchman has served as President and Chief Executive Officer and has been a member of Mustang’s Board of Directors since April 2017. Dr. Litchman joined Mustang from Arvinas, LLC, where he served as President and Chief Executive Officer. While at Arvinas, Dr. Litchman oversaw the advancement of the company’s pipeline of protein-degradation therapeutics for the treatment of cancers and other diseases toward Investigational New Drug applications, as well as the execution of multi-target discovery collaborations with Merck and Genentech. Prior to Arvinas, Dr. Litchman spent more than 18 years with Novartis Pharmaceuticals Corporation, where he held positions of increasing responsibility related to the development of Novartis’ oncology pipeline. Most recently, Dr. Litchman served as Senior Vice President and Executive Global Program Head, CTL019, Cell & Gene Therapies Unit, where he led a collaboration with the University of Pennsylvania investigating chimeric antigen receptor modified T cells (CAR Ts) directed against CD19 on B cell malignancies. Prior to the CTL019 collaboration, Dr. Litchman served as Novartis’ Vice President and Head, Oncology Business Development & Licensing. Earlier in his career, Dr. Litchman was a senior equity analyst at Ursus Capital and directed oncology / immunology clinical research at Hoffmann-La Roche Inc. Dr. Litchman received his M.D. from Yale University School of Medicine, and his B.A. from Princeton University. He completed his internal medicine residency and hematology-oncology fellowship at New York-Presbyterian Hospital / Weill Cornell Medical Center.
Brian Achenbach, M.B.A.
Senior Vice President of Finance & Corporate Controller
Mr. Achenbach has served as Senior Vice President of Finance & Corporate Controller since March 2019 after joining Mustang Bio in October 2017 as Vice President of Finance & Corporate Controller. Prior to Mustang, Mr. Achenbach served as Vice President & Corporate Controller at Amerigen Pharmaceuticals, where he oversaw finance and accounting functions as the company established itself as a commercial organization in the U.S. and China. Prior to Amerigen, Mr. Achenbach served as Vice President of Finance for the Americas and Vice President of Global Financial Planning & Analysis at ConvaTec, a global medical products and technologies company, where he led finance and accounting operations in the U.S., Canada and South America. Earlier in his career, Mr. Achenbach held roles of increasing responsibility in finance and accounting at Mylan, Andrx (acquired by Watson Pharmaceuticals) and IVAX (acquired by Teva Pharmaceuticals). Mr. Achenbach holds an M.B.A. in finance from Roosevelt University in Chicago and a B.A. in economics from the University of Florida in Gainesville.
Knut Niss, Ph.D.
Chief Technology Officer
Dr. Niss has served as Chief Technology Officer since March 2018. Dr. Niss joined Mustang in March 2017 as Vice President of Operations, where he initiated and oversees the establishment of Mustang’s cell therapy manufacturing facility. Prior to Mustang, Dr. Niss was Cell Therapy Asset Leader at Biogen, where he oversaw CMC-related activities for gene-edited hematopoietic stem cell and lentiviral gene therapy programs for sickle cell disease and hemophilia, respectively. Earlier in his career, Dr. Niss was Senior Technical Project Leader at Novartis’ cell therapy manufacturing facility in Morris Plains, New Jersey, where he directed the transfer and implementation of the CTL019 process from Penn to Novartis. He also served as Senior R&D Program Manager at EMD Millipore, where he established processes for the large-scale expansion of adult and pluripotent stem cells. Dr. Niss began his career in senior research positions in Pfizer’s Regenerative Medicine and Immunology groups. He holds a Ph.D. in molecular biology from Humboldt University of Berlin, and an M.S. in microbiology from the University of Göttingen in Germany. Dr. Niss completed his postdoctoral research at Boston Children’s Hospital and the Dana-Farber Cancer Institute.
Debra Manning, SPHR
Vice President of Human Resources
Debra Manning joined Mustang Bio as Vice President Human Resources in 2019. Ms. Manning has more than 20 years of HR leadership experience leading the human resources function in biotechnology, clinical diagnostics and medical device environments. She has developed and implemented key HR programs and practices requiring in-depth knowledge and practical experience in HR strategy, organizational development, talent acquisition, benefits and compensation, labor law, and employee relations. Prior to joining Mustang, Ms. Manning held HR leadership positions at LFB USA, Stratus Technologies, Magellan Biosciences and ESA Biosciences. She attended Northeastern University and received her SPHR Certification in 2011.
Greg Furrow, M.S., FRQA
Vice President of Quality
Greg Furrow joined Mustang Bio in January 2019 as head of Quality. He is responsible for leading the Quality Organization inclusive of Clinical Quality Assurance, Manufacturing Quality Assurance, Quality Control Chemistry, Microbiology and Raw Material, and Quality Systems in compliance with Food and Drug Administration (FDA) current Good Manufacturing Practices (cGMP), Good Clinical Practices (GCP), Good Laboratory Practices (GLP), and current ICH requirements.
Previously, Greg was Vice President of Quality and Compliance at Southern Research, an independent, 501(c)(3) nonprofit, scientific research organization where he was responsible for Quality Assurance, Bio-safety, Environmental Health and Safety, ISO-9000 Quality Systems Management, Information Technology (IT), Human Resources (HR), Export Control and Government Security.
Prior to Southern Research, Greg was Vice President of Quality and Regulatory Compliance at WIL research (now part of Charles River), a global CRO supporting the pharmaceutical, chemical and agrochemical industries where he was responsible for global Quality Assurance (GLP, GCP and cGMP) and Environmental Health and Safety.
Greg received his B.S. and M.S. from the University of Maryland at College Park. He is a past president of the Society of Quality Assurance, an honorary life Fellow of the Research Quality Association, a lecturer in Purdue University’s Regulatory and Quality Compliance graduate program and he is the EPA industry representative to the OECD GLP discussion group.
James Edinger, Ph.D.
Vice President of Preclinical Sciences
Dr. Edinger has served as Vice President of Preclinical Sciences since September 2019. In this capacity, he oversees Mustang’s Research, Translational, Analytical and Process Development activities. Prior to Mustang, Dr. Edinger was Senior Director of Integrative Research and Strategy at Celularity, focused on scientific oversight of Intellectual Property, Research, Translational and Process Development in a matrixed environment, as well as driving scientific due diligence of external opportunities. Research efforts focused on developing products in several areas of cellular therapeutics, including placental mesenchymal stem cells, T cells, NK cells, CAR-T cells, CAR-NK cells and genetic modifications thereof. He previously served as Director of Research Strategy and Innovation at Celgene Cellular Therapeutics, leading Intellectual Property, Research, Translational and Process Development for an autologous HPV antigen specific T cell product in early development. His early career included academic appointments at Columbia University and Hunter College of CUNY, developing research programs in mouse and human immunology. Dr. Edinger holds a Ph.D. in Biochemistry/Chemistry from the University of Maryland, Baltimore County, and he completed his postdoctoral research at Weill Cornell Medical College in New York City.